Jonathan Bell
Expanding access to monoclonal antibody-based products: a global call to action | Wellcome and IAVI
“Right-sized” efficient multi-product manufacturing | NASEM Workshop on Technical & Regulatory Barriers to Innovations in Pharmaceutical Manufacturing
The influence of domestic manufacturing capabilities on biologic pricing in emerging economies | Nature Biotechnology
How to make biopharmaceuticals quickly in small batches | NIH Director’s Blog
Today, vaccines and other protein-based biologic drugs are typically made in large, dedicated manufacturing facilities. But that doesn’t always fit the need, and it could one day change. A team of researchers has engineered a miniaturized biopharmaceutical “factory” that could fit on a dining room table and produce hundreds to thousands of doses of a needed treatment in about three days.
On-demand manufacturing of clinical-quality biopharmaceuticals | Nature Biotechnology
Fast, nimble, and on demand: the pursuit of a new way to mass produce medicines | STAT
Today there’s essentially one model for drug production: make as much as possible. But J. Christopher Love, a professor of chemical engineering at the Massachusetts Institute of Technology, has spent the last five years pursuing a different vision: a desktop drug manufacturing process that would be fast and nimble enough to help combat a small disease outbreak, treat an unusual cancer, or replace a rare enzyme.
This miniature drug factory fits on a few lab benches | Nature
An all-in-one bench-top system can churn out hundreds or thousands of doses of a medically useful protein in a few days — and can easily switch to manufacturing other proteins.